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Semaglutide vs. WAYT-less™ vs. Metformin: Why These Weight Loss Medications Are So Popular in 2023

<p>Semaglutide vs. WAYT-less™ vs. Metformin: Why These Weight Loss Medications Are So Popular in 2023</p>
Amy Brodsky Picture of Amy Brodsky

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Written by our editorial team.

Last Edited 6 min read

There are many weight loss medications on the market. Many of these medications are intended strictly for weight loss, but there are also diabetes drugs that have the added benefit of causing weight loss. What are these drugs, and how do they work? Semaglutide, WAYT-less™, and Metformin are all drugs that help you lose weight.


Semaglutide is an injection medication that is used to treat type 2 diabetes. Semaglutide is marketed under the names Ozempic, Wegovy, and Rybelsus. While it treats diabetes, Semaglutide is also used to treat obesity. This drug first came on the market in 2012. According to experts, Semaglutide facilitates weight loss and helps you maintain that weight loss long-term.

Semaglutide works in several ways. This medication triggers the pancreas to release the proper amount of insulin when blood sugar levels are elevated. Insulin moves sugar from the blood and distributes it to other bodily tissues. Once this sugar moves into other tissues in the body, it is utilized as energy.

Semaglutide is an injectable medication dispensed under the skin once per week. According to the Mayo Clinic, Semaglutide treats diabetes with the added benefit of causing weight loss. However, it is crucial to follow specific criteria when taking this medication. You should check your blood sugar regularly, "especially before and after meals." Additionally, you should check your blood sugar before you go to bed. This decreases your chances of having low blood sugar.

There are particular guidelines when it comes to food as well. If your doctor creates a meal plan for you, you must follow this plan. This is essential to control your diabetes. It also ensures that the medicine works like it's supposed to. For Semaglutide to be effective, you must implement a regular exercise routine. You should also test your urine and blood regularly, as advised.

As a GLP-1 receptor agonist or glucagon-like peptide-1 receptor agonist, Semaglutide suppresses appetite when it is given at higher doses. When it is dispensed in a higher amount, Semaglutide manipulates centers in the brain, thus suppressing appetite. Semaglutide lowers your body weight by reducing hunger and appetite. This makes you feel full and reduces your cravings for food. This drug also alters your food preferences and limits your energy intake.

Studies have found that a once-weekly dose of 2.4 milligrams controls eating and promotes gastric emptying, a process in which the stomach moves its contents to the duodenum. The duodenum is the first portion of the small intestine. The duodenum further digests food that comes from the stomach. It absorbs minerals, carbohydrates, proteins, and fats. Additionally, the duodenum absorbs water from the food you eat so that the body can absorb both water and other minerals.

According to a clinical trials study, the average weight loss achieved in the STEP 1 study of Semaglutide for weight loss was 14.9% of the initial body weight over 68 weeks. Another factor when considering Semaglutide drugs for weight loss is the cost, which costs over $1,000 on average.

However, another drug prides itself on its ability to cause weight loss. WAYT-less™, a weight loss program designed by Nu Image Medical, has several benefits.


WAYT-less™ is a combination of three different medications. These three medications are AcarboseOrlistat, and Low Dose Naltrexone. When combined, these three medications may help you lose weight. This medication is very beneficial. You take two daily doses of WAYT-less™ and see the pounds melt off.

So, what exactly do the three medications that comprise WAYT-less™ do? Acarbose is a prescription drug that blocks carbohydrate absorption. When it gets into your system, Acarbose slows your digestion of carbohydrates. This controls blood sugar levels. Acarbose has been used as an adjunctive medication when patients implement a healthy diet and reduce the consumption of carbohydrates.

As one of the best-performing weight loss programs on the market, this program is very effective because all of the components or ingredients help cause weight loss. According to experts, Orlistat, one of the drugs that makes up WAYT-less™, works by decreasing the volume of dietary fat absorbed by your intestines. Low Dose Naltrexone causes weight loss by controlling hunger and cravings. Low Dose Naltrexone also treats opioid and alcohol use disorders. According to experts, Low Dose Naltrexone is also a treatment for chronic pain.

According to, WAYT-less™ is currently a top-of-the-line weight loss program. This program improves digestion, reduces appetite and cravings, and increases energy levels. In addition, WAYT-less™ decreases body mass and lowers insulin resistance. One of this product's most significant benefits is that it reduces fat and makes you feel healthier. A doctor prescribes WAYT-less™. You may start seeing results in as little as one week.

WAYT-less™ is guaranteed to work within the first 90 days of taking the medication under your doctor's direction. If you do not lose weight within your first 90 days of taking it, your money will be refunded. Only patients taking WAYT-less™ can receive a refund. A one-month supply costs $299.00. Additionally, Nu Image Medical's internal studies show that patients lost an average of 17.8 pounds in 30 days.

If you are interested in this medication, you can complete a medical intake form. A physician will review your information and determine which products best meet your medical needs. WAYT-less™ is very effective, especially when combined with a healthy diet and a regular exercise routine. However, exercise is optional for this product to be effective. WAYT-less™ is one of Nu Image Medical's most popular products.

Metformin is another effective treatment for weight loss. 


As one of the world's most common diabetes medications, Metformin is an excellent treatment option for those with type 2 diabetes. Metformin helps you manage your glucose levels. Although this drug was designed to treat diabetics, it can also help you lose weight. Studies have proven Metformin's effectiveness. A survey conducted in 1998 found that Metformin is effective in causing weight loss in obese individuals with non-insulin-dependent diabetes mellitus (NIDDM).

Metformin suppresses your appetite, by increasing the body's sensitivity to hormones such as insulin and leptin. Leptin is in charge of telling your body when it is full and should stop eating, so increased sensitivity to this hormone can result in you feeling less hungry.

The result is a leaner form and a lower number on the scale. According to experts, weight loss on Metformin is inconsistent; consequently, people are taking the drug off-label. Although effective as a weight loss tool, Metformin has not been approved by the FDA for weight loss. Weight loss is simply a side effect. Metformin is relatively inexpensive. A monthly prescription for a 60 or 1000-milligram tablet costs roughly $20. That equals a little over 30 cents for one pill. While this is beneficial, it can take a long time to see weight loss results. However, a simple question remains: Should you take Metformin to lose weight? 

As an antihyperglycemic drug that lowers blood glucose levels, Metformin reduces the amount of glucose that the liver sends into the body. This causes insulin in the body to work more effectively. This drug is taken in tablet form. Metformin affects people differently. It works for weight loss by reducing the amount of insulin circulating through the blood. As a result, it reduces the amount of glucose stored as fat.

In conclusion, while Semaglutide, WAYT-less™, and Metformin are effective for weight loss, it is essential to note the key differences between these weight loss programs. Is one more effective than the other? And most importantly, which one is the best?

Semaglutide medications such as Ozempic, is an injection medication that is dispensed once a week, while Metformin is an oral pill taken twice daily. WAYT-less™ has three medications that are split into two daily doses: A tablet containing Orlistat and Acarbose and a tablet containing Low Dose Naltrexone. It’s that simple, just stick to the basics. These drugs have more benefits than you would imagine. Its trio combination of drugs makes it highly effective.

All these medications control blood sugar levels. However, the way they work is different. According to K Health, Semaglutide is a lot like the hormone GLP-1, which occurs naturally in the body. Semaglutide slows digestion, triggers insulin release, and reduces the amount of glucose the liver "releases." 

Metformin reduces hunger, but not in the same way as other drugs. Metformin affects the part of the brain that regulates your appetite and desire for food. This medication causes people to eat less at meal times. This forces you to have a better balance of glucose and insulin.

Acarbose, one of the medications that makes up WAYT-less™, is a prescription medication carbohydrate blocker. Carbohydrates lead to weight gain, so Acarbose is very effective and causes weight loss. At the same time, it's important to remember that neurochemicals play a role, too. Low Dose Naltrexone triggers a chemical reaction that manipulates two parts of your brain. These include the reward system and the hunger center. Meanwhile, orlistat will help with appetite suppression, regulate your blood sugar, block the absorption of fats, and help to lower lipids.

Eating a low-calorie diet is beneficial while taking this medication. In addition, WAYT-less™ has risen above its competitors and remains highly popular in the weight loss community. 

When it comes to weight loss, you have a lot of options available to you. However, these three options yield positive results.



21 Sources

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This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your physician about the risks and benefits of any treatment. Nu Image Medical may not offer the medications or services mentioned in this article.