What is Orlistat?
Orlistat, a lipase inhibitor, works by preventing some of the fats in food from being absorbed in the intestines. When coupled with a low-calorie diet and exercise program, it promotes weight loss. Prescription Orlistat (Xenical®) is also used after weight loss to keep people from gaining back the weight they lost.
How does Orlistat work?
The Science
Orlistat (Xenical®) works by inhibiting gastric and pancreatic lipases, the enzymes that break down triglycerides in the intestine. Triglycerides are not absorbed and are eliminated via feces, resulting in a caloric deficit that promotes weight loss.
Benefits
Orlistat (Xenical®) blocks the enzymes that digest fat. It effectively lowers blood lipids, may help regulate blood pressure, and improves insulin sensitivity. Coupled with a low-calorie diet and exercise program, Orlistat (Xenical®) causes more weight loss than dietary modifications and exercise alone.
Side Effects
Orlistat (Xenical®) can cause gas, bloating, diarrhea, and skin rash or itching.
See your physician if you develop abdominal pain, vision changes, eye discomfort, depression, mood changes, or ear
buzzing.
Talk to your physician for additional information or concerns.