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Best Time of Day to Take Enclomiphene

Best Time of Day to Take Enclomiphene
Dr. Constance Odom, MD
Dr. Constance Odom, MD
4 months ago / 8 min read

Enclomiphene is a medication commonly prescribed to treat male hypogonadism by increasing testosterone levels. When taking any medication, timing can significantly impact its efficacy and minimize side effects. Medical experts typically recommend taking enclomiphene between 7:00 a.m. and 10:00 a.m. each day to align with the natural peak in testosterone levels during the morning hours. Some individuals may benefit from twice-daily dosing, as recommended by their healthcare provider.

How Enclomiphene Works

Enclomiphene is a selective estrogen receptor modulator (SERM) that works by blocking estrogen receptors in the brain. This action stimulates the hypothalamus to release more gonadotropin-releasing hormone (GnRH), which then prompts the pituitary gland to produce more luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones increase the production of testosterone in the testes.

Morning vs. Evening Dosing | What is the best time of day to take enclomiphene?

Morning Dosing:

  • Pros: Incorporates easily into your morning routine, which can aid in consistent usage. It may also reduce the likelihood of sleep disturbances, especially if you are sensitive to medications.

  • Cons: Any mild side effects could potentially occur during the daytime, affecting daily activities.

Evening Dosing:

  • Pros: Aligns well with your evening routine and can be simpler to remember, particularly if mornings are busy.

  • Cons: While uncommon with enclomiphene, there is a slight possibility of experiencing sleep disturbances.

Personalized Advice

Ultimately, the best time of day to take enclomiphene can vary from person to person.

There is no one-size-fits-all answer to the best time of day to take enclomiphene, but consistency and personal preference play key roles. Whether you choose to take it in the morning or evening, the most important factor is to stick to the same time each day to ensure optimal results.


This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your physician about the risks and benefits of any treatment. Nu Image Medical may not offer the medications or services mentioned in this article.

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