Founded 2004 · Online since 2008 Pioneering telehealth.
Available in all 50 states.

Languages

Menu

Weight loss

Hormones

Sex

EXPLORE

Login

Welcome back

or

A quick and secure way to access your account—no password needed.

Growth Hormone "Boosters" Explained: HGH, Sermorelin, and Supplements

Constance Tambakis-Odom, MD
Constance Tambakis-Odom, MD / Reviewed January 2025 / 7 min read

Search for "growth hormone booster" and you will find prescription drugs, compounded peptides, supplement powders, and vials sold for "research" all presented side by side, as if they were versions of the same thing. They are not. Each one is regulated differently, and some should be avoided altogether. This guide sorts them into four groups so you know what you are looking at. It is educational and does not replace medical advice.

Growth hormone in brief

Growth hormone is made by the pituitary gland, a small gland at the base of the brain. The body releases it in pulses, mostly during deep sleep, in response to signals from another part of the brain. It plays a role in growth during childhood and in metabolism throughout life. Production naturally declines with age.

A true growth hormone deficiency in adults is a medical diagnosis. It usually follows damage to the pituitary gland from a tumor, surgery, radiation, or injury, and it is confirmed with specialized testing.

Group 1: Prescription human growth hormone

Human growth hormone, known by its drug name somatropin, is an FDA-approved injectable medication. It is approved for specific conditions, including diagnosed growth hormone deficiency.

One point sets it apart from most prescription drugs. Under federal law, HGH may only be distributed for uses that have been authorized, which means prescribing it for anti-aging, bodybuilding, or athletic performance is not permitted. A clinic offering HGH for those purposes is a warning sign.

Group 2: Prescription peptides such as sermorelin

Sermorelin is a different kind of medication. It is not growth hormone. It is a peptide modeled on the natural signal that tells the pituitary gland to release its own growth hormone.

Sermorelin is available by prescription only. The versions prescribed today, including those available through Nu Image, are compounded by state-licensed pharmacies. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.

Federal rules on which peptides pharmacies may compound have been under active review, and the status of individual substances has changed more than once. Ask your provider about the current status of anything prescribed to you.

Group 3: Over-the-counter "HGH booster" supplements

These are pills and powders, usually blends of amino acids and herbal ingredients, sold without a prescription. They do not contain growth hormone.

Dietary supplements are not approved by the FDA, and they are not evaluated for effectiveness before they go on sale. A label that says "supports HGH" has not been checked by any regulator. If you take one, tell your provider, since some ingredients can interact with medications.

Group 4: "Research use only" peptides sold online

Some websites sell peptide vials labeled "for research purposes" or "not for human consumption" directly to consumers. This group carries the most risk.

These products are not prescribed, are not made under pharmacy standards, and have no verified identity, strength, or sterility. The FDA has warned companies that market unapproved drugs this way. They should not be injected or used by anyone.

How to tell the groups apart

Ask four questions about any product:

  1. Does it require a prescription? Groups 1 and 2 do. Groups 3 and 4 do not.
  2. Who made it? A legitimate prescription comes from a licensed pharmacy that you can identify.
  3. Is it FDA-approved, compounded, or neither? You are entitled to a clear answer.
  4. Did a licensed provider review my health history first? If not, walk away.

Habits linked to normal growth hormone rhythm

Because growth hormone is released mainly during deep sleep, regular and sufficient sleep is part of the body's normal pattern. Vigorous exercise and a healthy body weight are also associated with normal release. These are general health habits worth keeping for many reasons, and none of them is a treatment for a medical deficiency.

What to discuss with a provider

If you are considering a prescription peptide, bring up:

  • Your reasons for asking and the symptoms you have noticed
  • Any history of cancer, thyroid problems, or pituitary conditions
  • Pregnancy or breastfeeding
  • All medications and supplements you take
  • Which format is being recommended and why
  • Possible side effects, such as reactions at the injection site, flushing, or headache
  • How follow-up will work

Getting an evaluation

Nu Image offers online evaluations with licensed providers. A provider reviews your health history and decides whether a prescription is appropriate. Where sermorelin is prescribed, it is available as an injection, a rapid-dissolve tablet, or a nasal spray, with dosing guidance and access to the care team.

 

This content is for educational purposes only and is not medical advice, diagnosis, or treatment. Compounded medications are prepared by state-licensed compounding pharmacies and are not reviewed or approved by the FDA for safety, efficacy, or quality. Prescription products require an online consultation with a licensed healthcare provider, who will determine whether a prescription is appropriate.

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your physician about the risks and benefits of any treatment. Nu Image Medical may not offer the medications or services mentioned in this article.

Explore more expert insights on treatments and wellness topics tailored to your health goals.