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Comparing Enclomiphene vs. Clomiphene for Low Testosterone

Comparing Enclomiphene vs. Clomiphene for Low Testosterone
Dr. Constance Odom, MD Picture of Dr. Constance Odom, MD

Medically reviewed by

Written by our editorial team.

Last Edited 4 min read

When it comes to managing low testosterone levels, two medications often come into focus: Enclomiphene and Clomiphene. Both have unique properties and potential benefits and understanding the differences between them can help make an informed decision tailored to individual patient needs.

Understanding Clomiphene

Clomiphene Citrate, commonly known as Clomid, has long been used in the treatment of infertility and low testosterone levels. It is a mixture of isomers, primarily Enclomiphene and Zuclomiphene.

  • Enclomiphene: The trans isomer that acts predominantly as an estrogen antagonist, which is beneficial for stimulating the release of gonadotropins and thereby boosting testosterone levels.

  • Zuclomiphene: The cis isomer, which has partial estrogenic effects and can potentially lead to side effects related to estrogen.

Introducing Enclomiphene

Enclomiphene Citrate is a newer agent derived from Clomiphene. It is essentially the pure trans isomer, without the estrogenic influences contributed by Zuclomiphene. This refined composition is suggested to be effective in boosting testosterone levels with a potentially lower risk of estrogenic side effects.

Key differences between Enclomiphene and Clomiphene

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Explore Nu Image's exclusive Enclomiphene treatment plan for low testosterone

Nu Image Medical offers enclomiphene as a transformative treatment for low testosterone. This option stimulates the body's natural testosterone production, providing an alternative to conventional hormone replacement therapies. Ideal for enhancing energy, mood, and overall well-being, enclomiphene is a game-changer in low testosterone management.

Remember, choosing between Clomiphene and Enclomiphene depends significantly on the patient's needs, sensitivities, and medical history. While both medications are effective for managing low testosterone, Enclomiphene's focused action can be advantageous for individuals prone to estrogenic side effects or those seeking a more precise treatment option.


This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your physician about the risks and benefits of any treatment. Nu Image Medical may not offer the medications or services mentioned in this article.