MK-677 is a long active orally bioactive agonist of the GHS-R1a. As such, binds to the same
receptor that GHRP2, GHRP6. It has shown to cause a predictable rise in IGF-1 but unlike
other GH secretagogues doesn’t help to decrease adipose tissue. It has been shown to increase
lean muscle mass and might be a good candidate for sarcopenic patients with low bone mineral
Your body releases growth hormone primarily through the action of two major hormones: growth hormone-releasing hormone and ghrelin. Ibutamoren (or as it’s becoming increasingly known as, MK-677) mimics ghrelin’s effects causing pulses of growth hormone to be released by your pituitary. Ibutamoren, unlike other growth hormone secretagogues, can be taken orally making it an attractive option for those apprehensive of injections.
Ibutamoren (MK-677) is a less specific growth hormone secretagogue by also acting on
adrenocorticotropic hormone (ACTH), cortisol and prolactin levels can
MK-677’s mechanism serves as the perfect pathway to a faster lean muscle development, increased strength, exercise tolerance, and a faster fat loss rate, with little or no muscle waste. It is fast and completely safe way of enhancing body composition without any negative side effects.
MK-677 is popular all of its positive health benefits such as:
Outside of the potential for cortisol and prolactin to elevate slightly, the most common side effects of ibutamoren (MK-677) therapy are the aforementioned appetite increase and drowsiness.
Ibutamoren (MK-677) is a capsule that is should be taken daily prior to going to sleep. The dosage should determined by your health care provider based on medical intake form.