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Peptides For A Better You: Ipamorelin

Peptides For A Better You: Ipamorelin

You’re researching anti-aging or restorative therapies for strength, energy, weight loss, libido, balance, or better healing. Maybe someone told you or maybe you “Googled it.” Regardless, you’ve run across the concept of using growth hormone or the peptides that release it.  One rises to the top: ipamorelin.  But what is ipamorelin?  How does it work? Is it safe? Where does one obtain it? Are there side effects? How the heck do you even pronounce it? Do you want to put something you can’t pronounce into your I-Only-Get-One-Body body? 

We’ll discuss these issues to help you understand ipamorelin and whether it’s an option for you. Let’s deal with the “What Have You Done for Me Lately” issue first.

What does Ipamorelin do for me?

Ipamorelin naturally increases your body’s production of growth hormone which benefits your body in several ways. For one thing, it increases testosterone production, which lags as we age. More balanced testosterone improves the effectiveness of muscle growth, increasing muscle mass and performance. Studies and anecdotal reports (informal testimony) show additional efficiencies in promoting fat burning, boosts in immunity, protection for organs like the liver, and reducing inflammation.  For you who can’t get to sleep or stay asleep, it improves sleep, making it deeper, longer and better quality than before use of ipamorelin. Don’t forget that it delivers improved quality of skin and hair, reduction of wrinkles, and obvious anti-aging effects. 

Benefits of Ipamorelin

  • Building lean muscle mass
  • Building strength in muscles
  • Decreasing body fat
  • Helping to regulate blood pressure
  • Helping to relieve pain
  • Improves joint and ligament repair
  • Improving sexual function
  • Improving sleep quality and because of that, mood
  • Promoting anti-aging effects
  • Promoting greater testosterone production
  • Promoting healthy skin
  • Promoting muscle definition, density, hardness, and contours
  • Regenerating vitality and energy
  • Regulating body temperature
  • Smoothing of wrinkles
  • Strengthening of bones 


So, what is Ipamorelin?  

Ipamorelin is a peptide.  A peptide is a chain of amino acids that are the building blocks for proteins and muscle fibers. Ipamorelin’s long description is Growth Hormone Releasing Peptide (for short, GHRP).  However, except for making the writing of this article easier, who cares about the acronyms? Ipamorelin is one of the safest and cleanest of the peptides that produce growth hormone, so is considered useful to more people with more conditions than some of the other GHRPs – er – peptides. Ipamorelin is noted for its enhanced specificity, which means it can be targeted. This peptide generates increased growth hormone secretion, but it does so without increasing appetite and less desired hormones like cortisol, acetylcholine, prolactin, and aldosterone, which other peptides in its class do. It has been very well-tolerated by various user groups.  

How does Ipamorelin work?

 Briefly, the ipamorelin peptide chain of amino acids work together to naturally help your pituitary gland produce growth hormone.  The pituitary gland sits in your brain behind your nose. It secretes the hormones that affect your thyroid, reproductive and adrenal systems.  Sometimes it is called the “master gland” because it helps so many body systems. It uses five amino acids that can stimulate growth hormone for strength, anti-aging, and healing.  These cellular changes can help with skin healing, increasing lean muscle, or reducing weight, among other benefits we’ll discuss in a minute.

You may remember it from middle school health class where they told you that it’s the gland that brings on puberty where girls begin growing breasts and boys’ voices start to get deeper. Oh, THAT one!

Is Ipamorelin safe?

Considered one of the cleanest and safest of the peptides, ipamorelin has been used with positive results in Europe and North America. To date it is the most effective generation of peptides (in this case, a polypeptide hormone) due to its ability to cause your body to most efficiently produce growth hormone. Lots of the side effects that can occur by Perhaps you’ve read about side effects of direct use of human growth hormone (HGH) including Carpal Tunnel Syndrome and swollen joints. But these do not exist from using ipamorelin, even after long term use.  

That efficiency is also higher since Ipamorelin blocks somatostatin (which inhibits growth hormone). Plus, when used in conjunction with other peptide versions, Ipamorelin actively delivers even better effect.

Ipamorelin is not only the most efficient, but also the safest and most selective growth hormone stimulant at the lowest doses. Even on higher doses or when over-dosed, Ipamorelin will only stimulate growth hormone. We repeat, it does not change the levels of prolactin, cortisol and other hormones that are less desirable. This feature makes Ipamorelin attractive for athletes and people losing weight as appears to be the current best option among all growth hormone releasing peptides (GHRPs).

What about Ipamorelin dosage?

A health or wellness practitioner should prescribe your ipamorelin dosage. Mixing and dosages are determined by various purposes.  A professional athlete needs a different amount than Aunt Tilly who is trying to lose weight or your upstairs neighbor who can’t sleep at night. The ipamorelin is concentrated and must be mixed with bacteria-free water before use.  The information provided here is general and for educational purposes.  Do not prescribe a dose for yourself. Let your professional health advisor determine the mixing, the dosage, the frequency, and timing.

Ipamorelin is taken by injection, because that is the most efficient and effective way to get it where it needs to go quickly. That means you, or someone else must give you a “shot” from syringes with small needles, like insulin syringes.  These are called “subcutaneous” syringes, which, when you translate the Latin, means you must put the medicine under the skin. Note the unit measuring marks printed on it.

 The dose is mixed just before you take it.  Your provider should give you either vials or ampules of bacteriostatic water when you purchase your ipamorelin. You will be trained on how to mix the correct ratio of water to ipamorelin for each dose, as well as how to do injections. This must be done with care to prevent contamination, but average people do it every day, so it is not rocket science. It is “I am taking good care of myself” science.  So, use good hygiene and be as precise as possible. 

Everybody’s body is different, so administer your ipamorelin as instructed by your professional health advisor. In very general terms, the dosage averages this pattern:

  • Dose per injection: 200mcg 
  • Injections per vial: 10 x 200mcg dosages 
  • Amount to Inject depends on your water-to-ipamorelin ratio. Examples are: 
  • If you mix 1ml of water, take a 200mcg dosage  at 0.10ml (10 units marked on the Insulin syringe). 
  • If you mix 2ml of water, take 200mcg at 0.20ml (or 20 units on the syringe) 
  • If you mix 3ml of water, take 200mcg at 0.30ml (the 30 unit mark on the syringe).
  • The injection frequency should be kept the same, building a routine. Best times are first thing in the morning, pre- or post-workout and before bed at night.
  • Beginners: 1 dose per day
  • Intermediate: 2 doses per day
  • Advanced: 3 doses per day

How do you say Ipamorelin?

Have you seen the ads and commercials where organic and natural foods marketers always promote the “If you can’t pronounce it, don’t put it in your body” idea? Sometimes that’s a good tactic, except that many of the most natural of ingredients in foods and health products don’t have a brand name or even a plain-English name.  They are natural or naturally occurring, but they are known to the medical, health, food, and agriculture industries by their Latin or scientific names.  Lactose, fructose, and glucose all are natural forms of sugar.  The Latin root “ose” is the give-away. But most of us aren’t doctors or scientists and we are not familiar with the Latin or scientific names for ingredients.  

In addition, we’ve all mispronounced a word or name before.  The people around us hide giggles or give each other the eye roll.  We assume they think we are ignorant. So, the next time we aren’t sure how to pronounce certain words, we are too embarrassed to ask the doctors or health professionals. Know this: asking to educate yourself is a far smarter move than choosing to remain ignorant because of a momentary embarrassment. Since we’ve been brave and asked, let’s have our answer!

How to say Ipamorelin: ipah-MORE-eh-lin. Practice reading that a few times, then stop looking at it and say it 20 times.  Hear the rhythm; tap it out; rap it: ipa-MORE-eh-lin / ipa-MORE-eh-lin / healin’ my body with / ipa-MORE-eh-lin. Now you are ready to discuss it with your doctor or health professional (or any snooty “pronunciation police” types)!

Why choose Ipamorelin over other peptides used for similar benefits?

Other peptides can have negative side effects. They can stimulate production of hormones you don’t need as well as the growth hormone you do need, such as cortisol (the stress hormone that increases weight gain around your middle) or prolactin (that can cause dizziness, nausea, and nasal stuffiness) to even more serious side effects that include joint pain or more rapid progression of repetitive stress injury. Your body can become so accustomed to certain stimulants that it takes more and more of them to create the original feeling or healing levels. Aside from the physical and mental advantages listed above, the characteristics prized from ipamorelin include the following qualities: 

  • Consistently produces only the growth hormone your body needs
  • More efficient than other peptides of its class
  • Faster recovery 
  • Helps suppress somatostatin (growth hormone inhibitor)
  • Long lasting effects
  • No extreme spikes in cortisol or prolactin
  • Doesn’t cause hunger spikes
  • Your body does not become less sensitive to it over time 


Where do I get my Ipamorelin?

To use ipamorelin for building muscle, losing weight, improved skin and hair, better sleep and more energy and vigor, your prescription can be filled by a compounding pharmacy, such as ours [link to your site]. Some health or wellness professionals will order your prescription, have it delivered to their facility or clinic, and you can pick it up there. Others will recommend that you take your prescription to the pharmacy(ies) they trust to compound the best quality product for you. Some clients purchase online—just be careful that you trust the source and the delivery method (mail, package delivery, etc.)

It is always best when you trust your health professional to guide you to a proper source for quality product that is produced in clean, safe environments.  Click here to enroll in our hormone replacement therapy program.

About the author

Dr. Constance Odom, MD

8 min read