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Growth Hormone Releasing Peptide 6 (GHRP-6)

Growth Hormone Releasing Peptide 6 (GHRP-6)

What is GHRP-6? 

GHRP-6, which stands for Growth Hormone Releasing Hexepeptide, is exactly that, a 28 amino acid peptide, and it works by sending signals to the pituitary gland to begin secreting growth hormone. 

For clarification's sake, the pituitary gland is a gland that is about the size of a pea, and it's situated in a bony hollow just behind the bridge of your nose, attached to the base of your brain by a thin stalk. It's often called the master gland due to it's controlling of several other hormone glands in the body, including the thyroid, adrenal, ovaries, and testicles. It secretes hormones from both the front part (anterior) and the back part (posterior) of the gland. Hormones are chemicals that carry messages from one cell to another through your bloodstream.

The hormone that is signaled to be released by GHRP-6 is the human growth hormone, also known as HGH, growth hormone, or just GH. HGH is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

Growth hormone releasing peptide-6, or GHRP-6, is basically an HGH secretagoue, or substance that promotes secretion. It has the potential to facilitate the effective increase in the levels of natural human growth hormone secretion in our body, and also can facilitate a sudden increase in body mass and bring about a massive reduction in body fat. 

While GHRP-6 lacks opioid activity, you tend to get a huge pulse (depending on the dosage) in your own GH levels, and you also get an increase in IGF-1, which stands for Insulin-like growth factor 1, which is primarily produced by the liver, and plays an important roll of growth in children, and has an anabolic effect in adults. Both the increase in GH and IGF-1 are highly desirable for athletes, bodybuilders, and even average joes who just want to improve their own physical fitness. 

GHRP 6 and its effects on your appetite

Many people have claimed that when you take GHRP-6, what soon follows is a very large and very intense increase in appetite about twenty minutes after the initial injection. This is caused by GHRP-6 mimicking the peptide Ghrelin, which is cardioprotective, can help protect cells against oxidative damage, can reduce inflammation and promote healing, and can even promote fat-burning in muscle. There is also some increase in cortisol production. GHRP-6 is effective in weight loss, as long as food intake is controlled while taking. 

On the other hand, the effects of taking more than 150mcg can be so strong that you may have a severe urge to stuff yourself with food, which can be a genuinely good thing during a hard bulk. Between the increase in appetite, and then anabolic effect and strength increase GHRP-6 may be the best peptide for a bulk. GHRP-6 has even been shown to improve skin tone. 

Because some GHRP's are equally effective as others in increasing GH but differ in effect on hunger or ACTH stimulation, it seems likely that there may be differences in ghrelin receptors between different tissues, or differences in function (for example with cofactors.) This is the most likely explanation for GHRP-6 being effective in stimulating hunger and helping heal tendinitis, while GHRP-2 stimulates hunger less and may have less value for healing.

As GHRP-6 directly affects the feedback loop which triggers changes in inhibition of the release of growth hormone, it can be used to restore the natural manufacturing of human growth hormone if natural secretion has been impaired because of long term artificial use. GHRP-6 has also had a reported effect on our nervous system, and are potentially capable of protecting neurons and increasing the strength of a person, and functions in a strikingly similar way to many steroids. 

GHRP 6 being used for Weight Loss?

GHRP-6 may be a newer drug on the market, but it certainly has caught the fancy of many, thanks to it's many enhancements and benefits. GHRP-6 administration has a strong fat lowering reputation, as mentioned above, making it great for people who are currently cutting weight, and also is helpful to people who are just weight conscious and looking to easily shed a few extra pounds. It also has the reputation of facilitating the increase of muscle mass and development, which really completes the fit look. Not only that, it actually has been claimed to increase stamina levels, and initiates better protection of the muscles and acts as an anti-inflammatory, which is crucial in the muscle recovery process. And thanks to it's IGF-1 secretion initiation, it helps you lose fat quicker and gain more strength as time passes.  Researchers around the globe suggest that the effectiveness of growth hormones depends a lot on the physical condition of the subject being administered with the drug. If the subject is obese, then there may not be the desired level of hormone secretion. Obesity seems to affect the effectiveness of GHRP-6 but if the subjects are not obese, the effects of this drug is likely to be the same for all gender or age groups, subject to the administered dosage.

GHRP 6 Side Effects

GHRP has a few side effects, and thus is not available without a prescription. This most common side effect of the drug is aggravated hunger, lactation in some users, and dizziness or light-headedness. 

Where can I buy GHRP 6 Online?

Just like the sale of any peptides online, GHRP 6 is often sold by many retailers that advertise the product to be for "Research Purposes Only" or "Not For Human Consumption". With that being said you should AVOID THESE RETAILERS at all cost.. The reason why is because these retailers are most likely selling you FAKE and Non-prescription grade GHRP 6. They are also doing so ILLEGALLY and are eventually shut down quite fast by the FDA and other government regulators of these products. Make sure to only purchase GHRP 6 from a licensed pharmacy, or threw a telemedicine company like Nuimage Medical.

So where can you buy GHRP 6 online? Click here and fill out our hormone replacement therapy form to learn more about obtaining your own vile of REAL Pharmaceudical grade GHRP 6.


GHRP-6, in conclusion, can effectively provide substantial increases in GH production, and is normally taken two to three times per day when blood sugar is not elevated. It's cost is usually moderate, and the only common potential side effect is that of an increased appetite. GHRP-6 also may provide benefits which GH does not, via its action at the ghrelin receptor in various tissues of the body.

About the author

Dr. Constance Odom, MD

6 min read